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Determining the functionality of the putative twin-arginine signal peptides of rhomboid proteases from Mycobacterium tuberculosis using the beta-lactamase reporter system
(Makerere University, 2020)
Rhomboid proteases are a group of integral membrane proteases present in several organisms. Because of their roles in many medically important processes, rhomboid proteases are potential drug targets. In Mycobacteria ...
Second-line drug resistance markers as indicators of time to sputum culture conversion among selected mycobacterium tuberculosis clinical isolates at the Uganda National Tuberculosis Reference Laboratory
(2022)
Drug-resistant TB continues to be a global public health crisis, with low treatment success rates for Multi Drug Resistant/ Rifampicin Resistant TB and Extensively Drug-Resistant TB. Achieving sustained bacteriological ...