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Association between malaria preventive treatment regimens in pregnancy and plasmodium falciparum drug resistance mediating polymorphisms in Busia district, Eastern Uganda
(Makerere University, 2020-06)
Intermittent preventive treatment in pregnancy (IPTp) with monthly sulfadoxine-pyrimethamine (SP) is recommended for malaria-endemic parts of Africa, but efficacy is compromised by resistance and, in recent trials, ...
Determining the functionality of the putative twin-arginine signal peptides of rhomboid proteases from Mycobacterium tuberculosis using the beta-lactamase reporter system
(Makerere University, 2020)
Rhomboid proteases are a group of integral membrane proteases present in several organisms. Because of their roles in many medically important processes, rhomboid proteases are potential drug targets. In Mycobacteria ...
The validity of novel biomarkers in improving prediction and diagnosis of coronary heart disease : a case of Mengo Hospital
(Makerere University, 2020-08-25)
Rising incidences of coronary heart disease is of great concern to public health especially among individuals without symptoms. This calls for accurate, early diagnosis which is the cornerstone for treatment, prognosis, ...
Characterisation of integrons which potentially mediate dissemination of antibiotic resistance in enterobacteriaceae isolated from healthy community members
(Makerere University, 2020-10)
Antibiotic resistance has become a global public health concern, by limiting the number of drugs used to treat bacterial infections. Antimicrobial resistance and multidrug resistance (MDR) therefore increase morbidity and ...
Prevalence of leptospirosis among patients attending renal and general outpatient units in Mulago Hospital, Kampala, Uganda
(Makerere University, 2020-12)
Leptospirosis is a zoonotic bacterial infection caused by spirochetes, which belong to the genus Leptospira. It is the most widespread zoonosis in the world and is considered a global public health threat. The dynamics of ...
Sero-prevalence and risk factors of peste des petit ruminants in Nakasongola and Nakaseke districts of Uganda
(Makerere University, 2020-01)
Peste des petits ruminants [PPR] is an acute highly contagious disease of small ruminants with high morbidity and mortality, leading to significant losses to farmers in Uganda. In Uganda, documented information on the ...