Plasmodium falciparum is a highly polymorphic parasite. This sometimes results in a high genetic diversity in the population and high complexity of infections among individuals. Although some studies indicate a relationship ...

This thesis focused on malaria vaccinology and employed reverse vaccinology and molecular techniques to predict potential vaccine candidates against P. falciparum malaria. Reverse vaccinology is fundamentally an in silico ...

Malaria, caused by Plasmodium falciparum (Pf), is one of the most important infections in African children and a leading cause of morbidity and mortality among refugees in sub-Saharan Africa. Uganda is one of the largest ...

Malaria remains a major public health concern especially among pregnant women and young children in sub-Saharan Africa. Few studies in Uganda have examined congenital malaria (CM) defined as presence of malaria parasites ...

Ferritin, a highly conserved iron storage protein that sequesters iron from pathogens including Plasmodium falciparum, is part of the acute phase response in malaria pathogenesis. Ferritin levels are elevated in severe ...

Plasmodium falciparum resistance mutations to aminoquinoline antimalarials are selected by prior drug use and may alter parasite fitness yet their associations with clinical malaria presentations are uncertain. ...