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Comparison of methods in the recovery of nucleic acids from archival formalin-fixed paraffin-embedded autopsy tissues
(Elsevier, 2010)
Archival formalin-fixed paraffin-embedded (FFPE) human tissue collections are typically in poor states of storage across the developing world. With advances in biomolecular techniques, these extraordinary and virtually ...
Quantitative assessment of the sensitivity of various commercial reverse transcriptases based on armored HIV RNA
(Public Library of Science, 2010)
Background: The in-vitro reverse transcription of RNA to its complementary DNA, catalyzed by the enzyme reverse transcriptase, is
the most fundamental step in the quantitative RNA detection in genomic studies. As such, ...
Zinc adjunct therapy reduces case fatality in severe childhood pneumonia: a randomized double blind placebo-controlled trial
(BioMed Central, 2012)
Background: Pneumonia is a leading cause of children’s deaths in developing countries and hinders achievement of the fourth Millennium Development Goal. This goal aims to reduce the under-five mortality rate, by two thirds, ...
Emergence of sickle cell gene through migration and intermarriage: A case study
(Africa Journal of Animal and Biomedical Sciences, 2009)
Sickle cell disease (SCD) is an inheritable disorder which is very common among persons of equatorial regions
including Africa. The evolution of SCD is linked to malaria endemicity in which sickle cell traits are selected
for ...