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The molecular biology of sulfadoxine-pyrimethamine drug resistance of plasmodium falciparum strains in Uganda
(Makerere University, 2007-08)
In November of 2000, Uganda changed its anti-malarial policy to replace chloroquine (CQ) with a combination of CQ and sulphadoxine–pyrimethamine (SP) as the first line agents. The idea of the combination was to delay the ...
Real-time imaging of the intracellular glutathione redox potential in the malaria parasite plasmodium falciparum
(Public Library of Science, 2013-12)
In the malaria parasite Plasmodium falciparum, the cellular redox potential influences signaling events, antioxidant defense, and mechanisms of drug action and resistance. Until now, the real-time determination of the redox ...
Role of Plasmodium Falciparuminfection In Transplacental Transfer Of Antibodies.
(Makerere University, 2021-04-22)
Even with several therapeutic interventions and a few vaccination strategies, Malaria still killed over 380,000 people in 2019alone,in Sub Saharan African Countries. One major cause is impaired transfer of antibodies from ...