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In vivo PPD reactivity and associated factors among HIV positive patients on HAART at the Makerere University Infectious Diseases Clinic.
(2009-08)
BACKGROUND:
It is estimated that a third of the world’s population is infected with tuberculosis (TB).
This epidemic is fueled by HIV, with reactivation rates of 8-10% / year and overall lifetime risk of 30% in HIV ...
Factors affecting utilization of natal services by HIV pregnant women in Jnja District, Uganda.
(2009-07)
BACKGROUND:
The Uganda MoH policy on PMTCT requires all HIV positive pregnant women to deliver in higher facilities to access nevirapine and modified obstetrical care in order to reduce MTCT. However, only 34% of the HIV ...
The spectrum of liver diseases in HIV infected individuals at an HIV treatment clinic in Kampala, Uganda
(Makerere University Medical School, 2008-03)
Background: Liver diseases are common in patients with HIV due to viral hepatitis B and C co-infections, opportunistic infections or malignancies, antiretroviral drugs and drugs for opportunistic infections. Objective: To ...
Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda
(Public Library of Science, 2012-07-02)
Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ...
Adherence to antiretroviral therapy in HIV-positive adolescents in Uganda assessed by multiple methods a prospective cohort study
(Adis, 2012-10)
Background: The effectiveness of traditional adherence measurements used in adolescent populations isdifficult to assess. Antiretroviral (ARV) adherence research among adolescents living with HIV in resourceconstrained ...
VS411 Reduced immune activation and HIV-1 RNA levels in 28 days: randomized proof-of-concept study for antiviral-hyperactivation limiting therapeutics
(PLoS One, 2012)
Background: A new class of antiretrovirals, AntiViral-HyperActivation Limiting Therapeutics (AV-HALTs), has been proposed as a disease-modifying therapy to both reduce Human Immunodeficiency Virus Type 1 (HIV-1) RNA levels ...
Impact of antiretroviral therapy on the incidence of Kaposi’s sarcoma in resource-rich and resource-limited settings
(Lippincott, Williams & Wilkins, 2012)
Purpose of review
Given the recent availability of antiretroviral therapy (ART) in resource-limited settings and the significant burden exacted by Kaposi’s sarcoma in these areas, we reviewed data regarding the impact of ...
Human immunodeficiency virus neurological complications: An overview of the Ugandan experience.
(Journal of NeuroVirology, 2005)
Sub-Saharan Africa, which has about 12% of the global population, is
home to almost 70% of individuals infected with human immunodeficiency
virus/acquired immunodeficiency syndrome (HIV/AIDS). A recent survey by
the ...
Steady-state pharmacokinetic comparison of generic and branded formulations of stavudine, lamivudine and nevirapine in HIV-infected Ugandan adults
(Oxford University Press, 2008-07-19)
Background: We aimed to compare the steady-state pharmacokinetic parameters and tolerability of Triomune 40w (stavudine 40 mg, lamivudine 150 mg and nevirapine 200 mg) and branded formulations of these drugs in HIV-infected ...
Immune reconstitution disease of the central nervous system
(Lippincott Williams & Wilkins, 2008)
Purpose of review
The purpose of this review is to examine the literature concerning immune reconstitution
disease associated with the central nervous system infections.
Recent findings
Immune reconstitution disease ...