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Coping with TB immune reconstitution inflammatory syndrome
(Expert Reviews, 2009)
The TB immune reconstitution inflammatory syndrome (IRIS) is a relatively frequent complication in HIV–TB-coinfected patients after they start highly active antiretroviral therapy (HAART). There are two forms of TB IRIS: ...
Rifampicin for continuation phase tuberculosis treatment in Uganda: a cost-effectiveness analysis
(Public Library of Science, 2012-06)
Background: In Uganda, isoniazid plus ethambutol is used for 6 months (6HE) during the continuation treatment phase of new tuberculosis (TB) cases. However, the World Health Organization (WHO) recommends using isoniazid ...
Health service delay and associated factors among pulmonary tuberculosis patients presenting to Mulago Hospital: a cross sectional study.
(2009-10)
Delay in the diagnosis of pulmonary tuberculosis (PTB) is common in many countries in sub-Saharan Africa. Timely diagnosis of active TB is particularly crucial to minimise not only morbidity and mortality in the community, ...
Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures
(BioMed Central, 2012)
Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ...
Existing capacity to manage pharmaceuticals and related commodities in East Africa: an assessment with specific reference to antiretroviral therapy
(BioMed Central, 2009)
Background: East African countries have in the recent past experienced a tremendous increase in the volume of antiretroviral drugs. Capacity to manage these medicines in the region remains limited. Makerere University, ...
Incidence and predictors of mortality and the effect of tuberculosis immune reconstitution inflammatory syndrome in a cohort of TB/HIV patients commencing antiretroviral therapy
(Lippincott Wilkins & Williams, 2011)
Background: Tuberculosis-HIV (TB-HIV) coinfection remains an
important cause of mortality in antiretroviral therapy (ART)
programs. In a cohort of TB-HIV–coinfected patients starting
ART, we examined the incidence and ...
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)
Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ...
Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources
(International Union Against Tuberculosis and Lung Disease, 2006)
Mycobacterium tuberculosis infection accounts for probably one third of human immunodeficiency virus (HIV)related immune reconstitution inflammatory syndrome (IRIS) events, particularly in developing countries where HIV ...
Factors influencing defaulting from tuberclosis treatment in Masaka District
(2004-06)
Background: Tuberculosis is a worldwide burden of infectious diseases About 2 Billion People are infected with TB every year and 3 Million people die. TB defaulting has been estimated to be 50-60% in Masaka district. ...
Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources
(International Union Against Tuberculosis and Lung Disease, 2006)
Mycobacterium tuberculosis infection accounts for probably one third of human immunodeficiency virus (HIV)related immune reconstitution inflammatory syndrome (IRIS) events, particularly in developing countries where HIV ...