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Effect of HIV-1 infection on malaria treatment outcome in Uganda patients
(Makerere University Medical School, 2007)
Background: Malaria and HIV-1 infection cause significant morbidity and mortality in sub-Saharan Africa. HIV-1 increases risk for malaria with the risk increasing as immunity declines. The effect of HIV-1 infection on ...
Daily co-trimoxazole prophylaxis in severely immunosuppressed HIV-infected adults in Africa started on combination antiretroviral therapy: an observational analysis of the DART cohort
(Elsevier, 2010-03-29)
Background: Co-trimoxazole prophylaxis can reduce mortality from untreated HIV infection in Africa; whether benefits occur alongside combination antiretroviral therapy (ART) is unclear. We estimated the effect of prophylaxis ...
Treatment of severe sepsis with Artemether-Lumefantrine Is associated with decreased mortality in Ugandan patients without malaria
(American Society of Tropical Medicine and Hygiene, 2009)
We enrolled 382 patients at two hospitals in Uganda in a prospective observational study of severe sepsis. Because artemisinins improve survival in murine sepsis models, we performed a post hoc analysis of the association ...