Search
Now showing items 1-10 of 15
The sensitivity and specificity of pleural fluid MTB-specific elispot assay among adults with suspected tuberculous pleurisy compared to pleural biopsy in Mulago Hospital
(Makerere University, 2009)
Introduction and rationale: Pleural effusions are a common reason for admission in Mulago hospital and tuberculosis is the most common infectious cause. The diagnosis of tuberculous pleural effusion with standard analysis ...
Assessment of diagnostic capacity of private practitioners in detection of tuberculosis in Juba City, South Sudan
(Makerere University, 2013)
Introduction
Tuberculosis (TB) remains a public health threat globally and is of major health concern in South Sudan. In 2012, TB notification rate for South Sudan was 88/100,000 for new cases and 96/100,000 for all ...
Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
(Public Library of Science, 2012-06-26)
Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ...
Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures
(BioMed Central, 2012)
Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ...
Nucleic acid amplification tests for diagnosis of smear-negative TB in a high HIV prevalence setting: a prospective cohort study
(Public Library of Science, 2011-01)
Background: Nucleic acid amplification tests are sensitive for identifying Mycobacterium tuberculosis in populations with positive sputum smears for acid-fast bacilli, but less sensitive in sputum-smear-negative populations. ...
Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources
(International Union Against Tuberculosis and Lung Disease, 2006)
Mycobacterium tuberculosis infection accounts for probably one third of human immunodeficiency virus (HIV)related immune reconstitution inflammatory syndrome (IRIS) events, particularly in developing countries where HIV ...
Tuberculosis immune reconstitution inflammatory syndrome in countries with limited resources
(International Union Against Tuberculosis and Lung Disease, 2006)
Mycobacterium tuberculosis infection accounts for probably one third of human immunodeficiency virus (HIV)related immune reconstitution inflammatory syndrome (IRIS) events, particularly in developing countries where HIV ...
Assessing the role of family support on non adherence to TB treatment by patients in Mulago hospital TB clinic
(Makerere University, 2013-08)
Background: Drug resistance among tuberculosis patients in sub-Saharan Africa is increasing mainly due to poor adherence to TB treatment despite various interventions aimed at improving treatment completion. Family support ...
Time to tuberculosis treatment default and its determinants among adult TB patients in Jinja District, A retrospective cohort study
(Makerere University, 2015-10)
Introduction: Whereas Tuberculosis is both preventable and curable, the disease remains a global health problem causing ill-health among millions of people each year and ranks as the second leading cause of death from an ...
Practices of diagnosis and treatment of pulmonary tuberculosis, associated factors, barriers and facilitators among private practitioners in Kampala, Uganda
(Makerere University, 2020-11)
Introduction: Globally, tuberculosis (TB) is a leading cause of morbidity and mortality accounting for an estimated 10.0 million new cases and 1.451million deaths in 2018. Uganda is one of the world’s high TB burden countries ...