Browsing College of Health Sciences (CHS) by Author "Nabatanzi, Rose"
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Bronchoalveolar lavage enzyme-linked immunospot for diagnosis of smear-negative tuberculosis in HIV infected patients
Cattamanchi, Adithya; Ssewenyana, Isaac; Nabatanzi, Rose; Den Boon, Saskia; Andama, Alfred; Worodria, William; Cao, Huyen; Huang, Laurence; Davis, J. Lucian; Miller, Cecily R. (Public Library of Science, 2012-06-26)Background: Peripheral blood interferon-gamma release assays (IGRAs) have sub-optimal sensitivity and specificity for diagnosis of active pulmonary tuberculosis (TB). However, assessment of local immune responses has been ... -
CDd4 t- cell immune responses in haart-treated hiv-infected adults who attain normal CD4 counts in a Ugandan cohort
Nabatanzi, Rose (Makerere University, 2014-05)Background: Majority of HIV-infected individuals who start HAART at CD4 counts <200 cells/µl show a marked CD4+T-cell increase to absolute CD4 counts above 500 cells/µl. The CD4+ T-cell count is the main measure for immune ... -
High CD56++CD16- natural killer (NK) cells among suboptimal immune responders after four years of suppressive antiretroviral therapy in an African adult HIV treatment cohort
Bayigga, Lois; Nabatanzi, Rose; Naluyima Sekiziyivu, Prossy; Mayanja-Kizza, Harriet; Kamya, Moses R.; Kambugu, Andrew; Olobo, Joseph; Kiragga, Agnes; Kirimunda, Sam; Joloba, Moses; Nakanjako, Damalie (BMC Immunology, 2014)Background: Up to 40% of HIV-infected individuals receiving Highly Active Antiretroviral Therapy (HAART) have poor CD4+ T-cell recovery. The role of natural killer (NK) cells in immune recovery during HAART is not well ... -
Impaired T-cell proliferation among HAARTtreated adults with suboptimal CD4 recovery in an African cohort
Nakanjako, Damalie; Ssewanyana, Isaac; Nabatanzi, Rose; Kiragga, Agnes; Kamya, Moses R.; Cao, Huyen; Mayanja-Kizza, Harriet (BMC Immunology, 2013)Background: Most HIV-infected subjects exhibit a progressive rise in CD4 T-cell counts after initiation of highly active antiretroviral therapy (HAART). However, a subset of individuals exhibit very poor CD4 T-cell recovery ... -
INNATE IMMUNE SYSTEM RECOVERY AFTER LONG TERM ANTIRETROVIRAL THERAPY IN AN AFRICAN COHORT
Nabatanzi, Rose (Makerere University, 2019-08-30)Background: Restoration of the immune system has been observed in many cohorts worldwide upon initiation of antiretroviral therapy. However, we have reported partial restoration of the T cell subset function despite seven ...