Browsing School of Veterinary Medicine and Animal Resources (SVAR) Collections by Author "Nerima, Barbara"
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Detection of mutant P2 adenosine transporter (TbAT1) gene in Trypanosoma brucei gambiense isolates from northwest Uganda using allele-specific polymerase chain reaction
Nerima, Barbara; Matovu, Enock; Lubega, George W.; Enyaru, John C. K (Wiley-Blackwell, 2007)objective To assess the application of allele-specific PCR (AS-PCR) as a fast, cheap and reliable method for detecting mutant TbAT1 associated with melarsoprol relapse in Trypanosoma brucei gambiense isolates from northwest ... -
Genotypic Status of the TbAT1/P2 Adenosine Transporter of Trypanosoma brucei gambiense Isolates from Northwestern Uganda following Melarsoprol Withdrawal
Kazibwe, Anne J. N.; Nerima, Barbara; de Koning, Harry P.; Maser, Pascal; Barrett, Michael P.; Matovu, Enock (Public Library of Science, 2009-09)Background: The development of arsenical and diamidine resistance in Trypanosoma brucei is associated with loss of drug uptake by the P2 purine transporter as a result of alterations in the corresponding T. brucei adenosine ...