Browsing School of Veterinary Medicine and Animal Resources (SVAR) by Subject "Melarsoprol"

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Genotypic Status of the TbAT1/P2 Adenosine Transporter of Trypanosoma brucei gambiense Isolates from Northwestern Uganda following Melarsoprol Withdrawal

Kazibwe, Anne J. N.; Nerima, Barbara; de Koning, Harry P.; Maser, Pascal; Barrett, Michael P.; Matovu, Enock (Public Library of Science, 2009-09)

Background: The development of arsenical and diamidine resistance in Trypanosoma brucei is associated with loss of drug uptake by the P2 purine transporter as a result of alterations in the corresponding T. brucei adenosine ...