Search

Now showing items 1-10 of 21

Tuberculosis-associated immune reconstitution inflammatory syndrome: case definitions for use in resource-limited settings

Meintjes, Graeme; Lawn, Stephen D.; Scano, Fabio; Maartens, Gary; French, Martyn A.; Worodria, William; Elliott, Julian H.; Murdoch, David; Wilkinson, Robert J.; Seyler, Catherine; John, Laurence; Lynen, Lut; Janoff, Edward N.; Gilks, Charles; Colebunders, Robert; van der Loeff, Maarten Schim (Elsevier, 2008-08)

The immune reconstitution inflammatory syndrome (IRIS) has emerged as an important early complication of antiretroviral therapy (ART) in resource-limited settings, especially in patients with tuberculosis. However, there ...

Comments on: predictors of immune recovery and the association with late mortalty while on antiretroviral treatment in Cambodia.

Hermans, S.M.; Sempa, J.; Castelnuovo, B.; Manabe, Y.C.; van Leth, F. (Elsevier, 2012)

We read with great interest the article by van Griensven and Thai, who report on the risk factors for late mortality after antiretroviral therapy (ART) initiation in a cohort of 2840 patients in Cambodia. The main risk ...

Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda

Hermans, Sabine M.; Castelnuovo, Barbara; Katabira, Catherine; Mbidde, Peter; Lange, Joep M. A.; Hoepelman, Andy I. M.; Coutinho, Alex; Manabe, Yukari C. (Lippincott, Williams & Wilkins, 2012-06-01)

Background: The World Health Organization recommends that treatment of tuberculosis ...

Sub-optimal vitamin B-12 levels among ART-Naïve HIV positive individuals in an urban cohort in Uganda

Semeere, Aggrey S.; Nakanjako, Damalie; Ddungu, Henry; Kambugu, Andrew; Manabe, Yukari C.; Colebunders, Robert (Public Library of Science, 2012-07-02)

Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression ...

Adherence to antiretroviral therapy in HIV-positive adolescents in Uganda assessed by multiple methods a prospective cohort study

Wiens, Matthew O.; MacLeod, Stuart; Musiime, Victor; Ssenyonga, Mark; Kizza, Ruth; Bakeera-Kitaka, Sabrina; Odoi-Adome, Richard; Ssali, Francis (Adis, 2012-10)

Background: The effectiveness of traditional adherence measurements used in adolescent populations isdifficult to assess. Antiretroviral (ARV) adherence research among adolescents living with HIV in resourceconstrained ...

Evaluation of portable point-of-care CD4 counter with high sensitivity for detecting patients eligible for antiretroviral therapy

Manabe, Yukari C.; Wang, Yaping; Elbireer, Ali; Auerbach, Brandon; Castelnuovo, Barbara (Public Library of Science, 2012-04-19)

Background: Accurate, inexpensive point-of-care CD4+ T cell testing technologies are needed that can deliver CD4+ T cell results at lower level health centers or community outreach voluntary counseling and testing. We ...

Impact of antiretroviral therapy on the incidence of Kaposi’s sarcoma in resource-rich and resource-limited settings

Semeere, Aggrey S.; Busakhala, Naftali; Martin, Jeffrey N. (Lippincott, Williams & Wilkins, 2012)

Purpose of review Given the recent availability of antiretroviral therapy (ART) in resource-limited settings and the significant burden exacted by Kaposi’s sarcoma in these areas, we reviewed data regarding the impact of ...

Palliative care in sub-Saharan Africa

Colebunders, Robert; John, L; Muganzi, A.; Lynen, L.; Kambugu, A. (2005-08-13)

We agree with Richard Harding and Irene Higginson (June 4, p 1971) and Anne Merriman and Manjit Kaur (p 1909) that improving palliative care services for people living with HIV/AIDS in sub-Saharan Africa is extremely ...

Adherence to anti-retroviral ttherapy among HIV infected mothers on option B plus aattending the Upper Mulago post natal clinic

Naiwumbwe, Halima K (Makerere University, 2014-06)

Background: Over 90% of the children living with HIV in Sub-Saharan Africa acquire the infection through mother-to-child transmission (MTCT). Elimination of MTCT (eMTCT) of HIV could be realized by country wide rollout of ...

Clinical spectrum, risk factors and outcome of immune reconstitution inflammatory syndrome in patients with tuberculosis-HIV coinfection

Worodria, William; Menten, Joris; Massinga-Loembe, Marguerite; Mazakpwe, Doreen; Bagenda, Danstan; Koole, Olivier; Mayanja-Kizza, Harriet; Kestens, Luc; Mugerwa, Roy; Reiss, Peter; Colebunders, Robert; The TB-IRIS study group (International Medical Press, 2012)

BACKGROUND: Here, we aimed to determine the clinical spectrum, predictors and outcomes of paradoxical tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) in a resource-limited setting. METHODS: In a ...