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When to switch for antiretroviral treatment failure in resource-limited settings?
(Lippincott Williams & Wilkins., 2007)
Thanks to the leadership of the World Health Organisation (WHO), and massive financial support from programmes such as the Global Fund and the US President’s Emergency Plan for AIDS Relief (PEPFAR), the number of HIV-infected ...
HIV immune reconstitution syndrome in sub-Saharan Africa
(Lippincott Williams & Wilkins, 2008)
Over the last 5 years, there has been remarkable progress
in providing HAART to patients in developing countries.
In sub-Saharan Africa alone, the number receiving antiretroviral
therapy (ART) has more than doubled in ...
Clinical features and serum biomarkers in HIV immune reconstitution inflammatory syndrome after cryptococcal meningitis: A prospective cohort study
(PLoS Medicine, 2010)
Background: Although antiretroviral therapy (ART) improves survival in persons with cryptococcal meningitis (CM) and AIDS, ART frequently elicits HIV immune reconstitution inflammatory syndrome (IRIS), an exaggerated and ...
The TB pandemic: an old problem seeking new solutions
(Blackwell, 2007)
Meya DB, McAdam KPWJ (Infectious Disease Institute, Kampala, Uganda). The TB pandemic: an old problem seeking new solutions (Review). J Intern Med 2007; 261: 309–329. Tuberculosis (TB) continues to kill more than 2 million ...
The International HIV Dementia Scale: a new rapid screening test for HIV dementia
(Lippincott Williams & Wilkins, 2005)
Objective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing ...
Pharmacokinetics of antiretroviral drug varies with formulation in the target population of children with HIV-1
(Clinical Pharmacology & Therapeutics (Nature Publishing Group), 2012-02-21)
The bioequivalence of formulations is usually evaluated in healthy adult volunteers. In our study in 19 HIV-1-infected Ugandan children (1.8–4 years of age, weight 12 to <15 kg) receiving zidovudine, lamivudine, and abacavir ...
Incremental yield of serial sputum cultures for diagnosis of tuberculosis among HIV infected smear negative pulmonary TB suspects in Kampala, Uganda
(PLoS ONE, 2012-05-22)
Background: Sputum culture is the gold standard for diagnosis of pulmonary tuberculosis (PTB). Although mostly used for research, culture is recommended by the World Health Organization for TB diagnosis among HIV infected ...
A Randomized controlled trial to evaluate the effectiveness of a board game on patients' knowledge uptake of HIV and sexually transmitted diseases at the Infectious Diseases Institute, Kampala, Uganda
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2012-03-01)
Background: As the number of HIV infections continues to rise, the search for effective health education strategies must intensify. A new educational board game was developed to increase HIV peoples' attention and knowledge ...
Prevalence and factors associated with cryptococcal antigenemia among severely immunosuppressed HIV-infected adults in Uganda: a cross-sectional study
(Journal of the International AIDS Society, 2012-03-14)
Background: Cryptococcal infection is a common opportunistic infection among severely immunosuppressed HIV patients and is associated with high mortality. Positive cryptococcal antigenemia is an independent predictor of ...
Integrating cryptococcal antigen screening andpPre-emptive treatment into routine HIV care
(Lippincott, Williams & Wilkins, 2012-04-15)
Cryptococcal meningitis is a leading cause of death in AIDS patients in sub-Saharan Africa. Cryptococcal antigen (CRAG) can be detected weeks before onset of symptoms, and those who are asymptomatic but CRAG positive have ...