Browsing Infectious Diseases Institute (IDI) Collections by Type
Now showing items 21-40 of 87
-
Developing independent investigators for clinical research relevant for Africa
(BioMed Central, 2012)Sustainable research capacity building requires training individuals at multiple levels within a supportive institutional infrastructure to develop a critical mass of independent researchers. At many African medical ... -
Effect of food on the steady-state pharmacokinetics of tenofovir and emtricitabine plus efavirenz in Ugandan adults
(Hindawi Publishing Corporation, 2012-02-20)We investigated the effect of food on the steady-state pharmacokinetics of a proprietary fixed-dose combination (FDC) tablet containing tenofovir disoproxil fumarate (TDF)/emtricitabine/efavirenz. Fifteen Ugandan HIV-1 ... -
The effects of an HIV project on HIV and non-HIV services at local government clinics in urban Kampala
(Biomed Central, 2011)Background: HIV/AIDS is a major public health concern in Uganda. There is widespread consensus that weak health systems hamper the effective provision of HIV/AIDS services. In recent years, the ways in which HIV/AIDS focused ... -
The epidemiology and clinical correlates of HIV-1 co-receptor tropism in non-subtype B infections from India, Uganda and South Africa
(Journal of the International AIDS Society, 2012-01-26)Background: The introduction of C-C chemokine receptor type-5 (CCR5) antagonists as antiretroviral therapy has led to the need to study HIV co-receptor tropism in different HIV-1 subtypes and geographical locations. This ... -
Etiology of pruritic papular eruption with HIV infection in Uganda
(American Medical Association., 200-12-01)Context A frequent cause of human immunodeficiency virus (HIV)–related morbidity in sub-Saharan Africa is a commonly occurring, intensely pruritic skin rash. The resulting scars are disfiguring and stigmatizing. Despite ... -
Evaluation of Dynabeads and Cytospheres Compared With Flow Cytometry to Enumerate CD41 T Cells in HIV-Infected Ugandans on Antiretroviral Therapy
(Lippincott Williams & Wilkins., 2008-07-01)Background: Laboratory-based monitoring of antiretroviral therapy is essential but adds a significant cost to HIV care. The World Health Organization 2006 guidelines support the use of CD4 lymphocyte count (CD4) to define ... -
Evaluation of portable point-of-care CD4 counter with high sensitivity for detecting patients eligible for antiretroviral therapy
(Public Library of Science, 2012-04-19)Background: Accurate, inexpensive point-of-care CD4+ T cell testing technologies are needed that can deliver CD4+ T cell results at lower level health centers or community outreach voluntary counseling and testing. We ... -
Free antiretrovirals must not be restricted only to treatment-naive patients: experience in Uganda suggests that restricting access is not the way forward
(Public Library of Science, 2005-10)No Abstract -
HIV Eosinophilic Folliculitis in Uganda
(American Medical Association (AMA), 2006) -
HIV immune reconstitution syndrome in sub-Saharan Africa
(Lippincott Williams & Wilkins, 2008)Over the last 5 years, there has been remarkable progress in providing HAART to patients in developing countries. In sub-Saharan Africa alone, the number receiving antiretroviral therapy (ART) has more than doubled in ... -
Immune reconstitution disease of the central nervous system
(Lippincott Williams & Wilkins, 2008)Purpose of review The purpose of this review is to examine the literature concerning immune reconstitution disease associated with the central nervous system infections. Recent findings Immune reconstitution disease ... -
Impact of antiretroviral therapy on the incidence of Kaposi’s sarcoma in resource-rich and resource-limited settings
(Lippincott, Williams & Wilkins, 2012)Purpose of review Given the recent availability of antiretroviral therapy (ART) in resource-limited settings and the significant burden exacted by Kaposi’s sarcoma in these areas, we reviewed data regarding the impact of ... -
The impact on nurses and nurse managers of introducing PEPFAR clinical services in urban government clinics in Uganda
(BioMed Central Ltd, 2011)Background: Improving provider performance is central to strengthening health services in developing countries. Because of critical shortages of physicians, many clinics in sub-Saharan Africa are led by nurses. In addition ... -
Improvement of the patient flow in a large urban clinic with high HIV seroprevalence in Kampala, Uganda
(International Journal of STD & AIDS, 2009)Antiretroviral treatment roll-out programmes in Africa often have difficulties to cope with the increasing number of clients. Based on the findings of a survey carried out in 2005 that showed long waiting times, innovative ... -
In reply to `Empirical tuberculosis treatment or improved diagnostics?'
(International Union Against Tuberculosis and Lung Disease, 2012-02-16)We read the article by Lawn and colleagues with great interest. Atypical presentation and limited diagnostic capability in resource-limited settings lead to delays in treatment that could contribute to high rates of ... -
Incremental yield of serial sputum cultures for diagnosis of tuberculosis among HIV infected smear negative pulmonary TB suspects in Kampala, Uganda
(PLoS ONE, 2012-05-22)Background: Sputum culture is the gold standard for diagnosis of pulmonary tuberculosis (PTB). Although mostly used for research, culture is recommended by the World Health Organization for TB diagnosis among HIV infected ... -
Integrating cryptococcal antigen screening andpPre-emptive treatment into routine HIV care
(Lippincott, Williams & Wilkins, 2012-04-15)Cryptococcal meningitis is a leading cause of death in AIDS patients in sub-Saharan Africa. Cryptococcal antigen (CRAG) can be detected weeks before onset of symptoms, and those who are asymptomatic but CRAG positive have ... -
Integration of HIV and TB services results in improved TB treatment outcomes and earlier prioritized ART initiation in a large urban HIV clinic in Uganda
(Lippincott, Williams & Wilkins, 2012-06-01)Background: The World Health Organization recommends that treatment of tuberculosis ... -
The International HIV Dementia Scale: a new rapid screening test for HIV dementia
(Lippincott Williams & Wilkins, 2005)Objective: HIV dementia is an important neurological complication of advanced HIV infection. The use of a cross-cultural screening test to detect HIV dementia within the international community is critical for diagnosing ... -
Is it safe to switch from stavudine to zidovudine after developing symptomatic hyperlactatemia?
(African Health Sciences, 2008-06)Introduction: In resource limited settings patients on antiretroviral treatment who develop stavudine induced hyperlactatemia are often switched to zidovudine on the basis of published studies that demonstrate that this ...