Browsing School of Medicine (Sch. of Med.) Collections by Subject "Sub-Saharan Africa"
Now showing items 1-20 of 25
-
The age-specific incidence of hospitalized paediatric malaria in Uganda
(BMC, 2020)Background: Understanding the relationship between malaria infection risk and disease outcomes represents a fundamental component of morbidity and mortality burden estimations. Contemporary data on severe malaria risks ... -
Antiretroviral therapy improves cognitive impairment in HIV individuals in Sub-Saharan Africa
(American Academy of Neurology (AAN), 2006)Abstract—Background: Highly active antiretroviral therapy (HAART) can improve cognitive performance in some patients with HIV-associated cognitive impairment in the United States. The effect of HAART on HIV dementia ... -
An assessment of implementation science research capacity in Uganda
(BioMed Central, 2021)Background: In Uganda and other resource-poor countries, relevant research findings face a tortuous path to translation into policy and routine practice. Implementation science (ImSc) research could facilitate faster ... -
Assisted partner notification utilization and associated factors among sexually active HIV positive adolescents aged 15-19 years at Baylor Clinic, Mulago Kampala
(Makerere University, 2023)Background: Whereas HIV Assisted Partner Notification (APN) is recommended by the World Health Organization for adolescents in SSA because of the high catch rate of new HIV positive cases among adults, no studies have been ... -
Association between indoor residual spraying and pregnancy outcomes: a quasi-experimental study from Uganda
(Oxford University Press, 2022)Background: Malaria is a risk factor for adverse pregnancy outcomes. Indoor residual spraying with insecticide (IRS) reduces malaria infections, yet the effects of IRS on pregnancy outcomes are not well established. We ... -
Ceftriaxone versus chloramphenicol for the treatment of severe pneumonia in children at mulago hospital: a randomised control trial.
(2007)Background: Acute lower respiratory tract infections are a leading cause of morbidity and mortality in sub-saharan Africa. The World Health Organisation (WHO) still recommends intravenous chloramphenicol for the treatment ... -
Comparison of buccal midazolam to rectal diazepam in the treatment of prolonged convulsions in children at Mulago Hospital
(2007-04)INTRODUCTION: Convulsions continuing for five minutes or longer are common in children in sub-saharan Africa and are medical emergencies. We compared the efficancy and safety of rectal diazepam and buccal midazolam in the ... -
Effect of blood storage age on the resolution of lactic acidosis in children with severe malarial anemia at Mulago Hospital.
(Makerere University, 2012)Background: Severe malarial anaemia requiring blood transfusion is a life threatening condition affecting millions of children in Sub-Saharan Africa. Up to 40% of children with severe malarial anemia have associated lactic ... -
Factors associated with adherence to anti-tuberculosis treatment among children attending TB clinics in Mulago Hospital, Nsambya Home Care and Kawempe (KCCA Health Centre).
(Makerere University, 2014)Introduction: Tuberculosis (TB) is a major cause of mortality and morbidity with about 8.8 million new TB cases globally in 2010.Uganda like most of Sub-Saharan Africa, has a high burden of TB and this is fuelled by the ... -
Frequency of and risk factors for HIV dementia in an HIV clinic in sub-Saharan Africa
(American Academy of Neurology, 2007)Objective: To measure the frequency and associated risk factors of HIV dementia in an HIV clinic in Kampala, Uganda. Methods: We systematically sampled 78 HIV-seropositive (HIV ) patients from an ambulatory HIV ... -
The influence of pre-hospital treatment of fever on severity of malaria among children 6-59 months presenting at Mulago Hospital: A case-control study.
(Makerere University, 2014)Introduction: Delivery of prompt and adequate treatment for malaria at the community level remains a strategy to reduce the burden of malaria in sub-Saharan Africa. As a result of this many patients with suspected malaria ... -
Low-level viraemia: An emerging concern among people living with HIV in Uganda and across sub-Saharan Africa
(AOSIS, 2022)Attaining viral load (VL) suppression for over 95% of the people living with HIV on antiretroviral therapy is a fundamental step in enabling Uganda and other sub-Saharan African countries to achieve global Sustainable ... -
Malaria diagnosed in an urban setting strongly associated with recent overnight travel: A case–control study from Kampala, Uganda
(2020)Malaria is frequently diagnosed in urban Kampala, despite low transmission intensity. To evaluate the association between recent travel out of Kampala and malaria, we conducted a matched case–control study. Cases were ... -
Methods to estimate baseline creatinine and define acute kidney injury in lean Ugandan children with severe malaria: A prospective cohort study
(BMC, 2020)Background: Acute kidney injury (AKI) is increasingly recognized as a consequential clinical complication in children with severe malaria. However, approaches to estimate baseline creatinine (bSCr) are not standardized in ... -
Neutrophil gelatinase-associated lipocalin is elevated in children with acute kidney injury and sickle cell anemia, and predicts mortality
(Elsevier, 2022)Urine neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker of acute kidney injury that has been adapted to a urine dipstick test. However, there is limited data on its use in low and-middle-income countries ... -
Outcomes and predictors of survival among children with hodgkin lymphoma at Uganda Cancer Institute
(Makerere University, 2022-11)Background: Hodgkin Lymphoma (HL) is one of the most curable childhood malignancies. HL represents 6% of all childhood cancers and has an incidence rate of 12 cases/million/year in the 0–14-year age group worldwide It has ... -
Prevalence and factors associated with congenital malaria in newborns aged 1-7 days attending Tororo District Hospital- Uganda.
(Makerere University, 2014)Introduction: Malaria is the most prevalent infection in Sub-Saharan Africa, accounting for a great degree of morbidity and mortality especially in the paediatric population. There is evidence to show that babies born to ... -
Prevalence and factors associated with malaria parasitemia in infants below 6 months of age on the out-patient clinic of Mulago Hospital
(2008-06)BACKGROUND: Malaria remains the most important parasitic cause of mortality and morbidity in infants in sub-saharan Africa. Previously it had been thought that malaria in infants below six months of age was infrequent in ... -
Prevalence, facilitators and barriers of HIV disclosure among boarding school adolescents on ART: The Baylor Uganda experience
(Makerere University, 2023)Background An estimated 1.7 million adolescents are living with HIV worldwide, with about 85% (1.5 million) of these in sub-Saharan Africa (SSA). Adolescents account for about 10% of all the new HIV infections and again, ... -
Prevalence, patterns and factors associated with ocular manifestations of type 1 diabetes mellitus among children and adolescents attending Mulago National Referral Hospital
(Makerere University, 2021-12)Background; Diabetes mellitus is a growing public health challenge in sub-Saharan Africa, Uganda inclusive, with an annual incidence of 6% in the Sub-Saharan Africa region, 3% in many countries and 77% in the European ...