Background: Subtypes A1, D and inter-subtype recombinants dominate the Uganda HIV-1 epidemic. This diversity has affected disease diagnosis and therapeutics. Predictive modeling could guide better understanding of the ...

Background: About a quarter of the world’s population has been infected with Mycobacterium tuberculosis, in immune compromised people like in HIV- infected persons, the risk of developing tuberculosis is 22 times higher. ...

Background: Seasonal influenza and coronaviruses both exhibit continual adaptive evolution during endemic circulation in the human population. The rapid evolution of human pathogenic RNA viruses can undermine the efforts ...

Background: Prostate cancer (PCa) remains the most common cancer among men in sub-Saharan Africa (SSA). Uganda has the highest incidence and mortality of PCa in the East Africa region. The overall survival of patients with ...

ABSTRACT Background: In 80–90% of HIV-1 discordant partners, infection of the naive partner always results from the successful transmission and propagation of a single virus variant, termed the Transmitter Founder (TF) ...

Introduction Methicillin resistant Staphylococcus aureus is defined as Staphylococcus aureus strain resistant to almost all Beta-lactams antimicrobial agents. The increased burden of methicillin resistant Staphylococcus ...

Background There were 19.3 million new cancer cases and 10 million cancer deaths which occurred in 2020. Compared to high-income countries cancer is a growing public health problem in sub-Saharan Africa, where mortality ...

Introduction:COPD is a chronic lung condition characterized by irreversible airflow obstruction and encompasses chronic bronchiolitis and emphysema. Cigarette smoking is the predisposing factor in over 50% of cases but ...