Search
Now showing items 1-3 of 3
Effect of vitamin d binding protein gene polymorphisms and vitamin d bioavailability on cathelicidin expression in tuberculosis infection and disease
(Makerere University, 2023-01)
Background: The human antimicrobial peptide cathelicidin (LL-37) is involved in host innate immunity by the after activation of Toll-like receptors (TLRs), resulting in direct killing of Mycobacterium tuberculosis (MTB). ...
Mycobacterium tuberculosis associated immune activation, inhibition and exhaustion profiling to predict active tuberculosis disease among presumptive tuberculosis participants and monitor anti-tuberculosis treatment response.
(Makerere University, 2023)
Globally, tuberculosis (TB) is the leading cause of mortality and morbidity especially among resource-limited populations including Uganda. This statistic is greatly fueled by the delay in diagnosis of the disease and ...
A comparison of frequencies and function of myeloid derived suppressor cells (MDSCS) IN TB/HIV co-infected and HIV mono-infected individuals in Uganda
(Makerere University, 2023)
Background
Myeloid-derived suppressor cells (MDSC) encompass a subset of myeloid cells, which suppress both innate and adaptive immune functions. These cells negatively regulate the immune function either by arginine ...