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Pulmonary dimorphic fungal infections in HIV infected patients with NON-TB chronic cough at Mulago Hospital, Uganda
(Makerere University, 2021-03)
Introduction: Dimorphic fungi cause infection following inhalation of spores (conidia) into the pulmonary system. In the lower respiratory tract the conidia transform into the yeast phase which are engulfed by alveolar ...
Motivation to participate in HIV/AIDS clinical trials among trial participants at joint clinical research centre, Lubowa, Wakiso district, Uganda
(Makerere University, 2021-03-10)
Background: Participation from diverse population groups in clinical trials is important but also,
allowing voluntary decision making is equally important. To understand the dynamics of
decision-making, contextual focus ...
Microbiome metatranscriptomics of the black soldier fly larvae gut for identification and functional characterization of lignocellulosic biomass-degrading microbes
(Makerere University, 2021-12)
Second-generation biofuel production has emerged as a sustainable and alternative energy option to the fast depleting, ecologically unfriendly petroleum-based fuels. Second-generation biofuels are produced from lignocellulosic ...
Prognostic factors for overall survival of patients with prostate cancer in Kyadondo county, Uganda
(Makerere University, 2021-02-24)
Background: Prostate cancer (PCa) remains the most common cancer among men in sub-Saharan Africa (SSA). Uganda has the highest incidence and mortality of PCa in the East Africa region. The overall survival of patients with ...
Vancomycin Resistance among Methicillin Resistant Staphylococcus aureus Isolates in Uganda.
(Makerere University, 2021-04-01)
Introduction Methicillin resistant Staphylococcus aureus is defined as Staphylococcus aureus strain resistant to almost all Beta-lactams antimicrobial agents. The increased burden of methicillin resistant Staphylococcus ...
Antibody responses to Mycobacterial glycans and glycolipids as potential correlates of protection from mycobacterium tuberculosis infection in BCG vaccinated children
(Makerere University, 2021-04-01)
Background: Globally, tuberculosis (TB) has remained the main cause of death from a single
infectious pathogen. The only licensed TB vaccine to date, BCG, has variable efficacy. We need
to understand the mechanism ...
Interferon Sensitivity Profiles of HIV-1 Transmitter Founder Viruses of Subtypes A, D and AD Recombinants in Uganda.
(Makerere University, 2021-02-08)
ABSTRACT
Background: In 80–90% of HIV-1 discordant partners, infection of the naive partner always results from the successful transmission and propagation of a single virus variant, termed the Transmitter Founder (TF) ...
Sputum microRNA profiles of treatment-naïve and patients on antituberculosis therapy in Mulago National Referral Hospital
(Makerere University, 2021-03-29)
Background: Worldwide, tuberculosis (TB) is the leading cause of death due to a single infectious
agent. This is attributed to the limitations of the current diagnostic tests in terms of sensitivity and
specificity. ...
Role of Killer-cell Immunoglobulin-like Receptors and Human Leukocyte Antigens in Transmission and Severity of Malaria in Uganda
(Makerere University, 2021-04-08)
Background
Malaria is a life-threatening disease caused by Plasmodium falciparum. In 2018, there were an estimated 228 million cases of malaria worldwide and 405,000 malaria deaths. Malaria burden is greatly affected by ...
Evaluation of quality of hepatitis B vaccines circulating on the Ugandan market
(Makerere University, 2021-04-28)
Vaccination is the greatest public health intervention in these modern times. Since the Ministry
of Health -Uganda rolled out the Hepatitis B vaccination program, there has been a continuous
decrease in the number of new ...