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Evaluation of capilia TB assay for rapid identification of mycobacterium tuberculosis complex in BACTEC MGIT 960 and BACTEC 9120 blood cultures

Muchwa, Christopher; Akol, Joseph; Etwom, Alfred; Morgan, Karen; Orikiriza, Patrick; Mumbowa, Francis; Odong, Paul R.; Kateete, David P; Eisenach, Kathleen D.; Joloba, Moses L. (BioMed Central, 2012)

Background: Capilia TB is a simple immunochromatographic assay based on the detection of MPB64 antigen specifically secreted by the Mycobacterium tuberculosis complex (MTC). Capilia TB was evaluated for rapid identification ...

A metabolic biosignature of early response to anti-tuberculosis treatment

Mahapatra, Sebabrata; Hess, Ann M.; Johnson, John L.; Eisenach, Kathleen D.; DeGroote, Mary A.; Gitta, Phineas; Joloba, Moses L.; Kaplan, Gilla; Walz, Gerhard; Boom, W. Henry; Belisle, John T. (BMC Infectious Diseases, 2014)

Background: The successful treatment of tuberculosis (TB) requires long-term multidrug chemotherapy. Clinical trials to evaluate new drugs and regimens for TB treatment are protracted due to the slow clearance of Mycobacterium ...