Isoniazid Preventive therapy Adherence and its associated factors Among HIV positive soldiers who are on ART at Bombo General military hospital, Uganda

Abstract

Introduction Uganda, like the rest of sub-Saharan countries is affected by the dual tuberculosis (TB) and HIV burden and is the seventh in 22 countries with the highest TB. Tuberculosis and HIV infections combined causes more adherence problems. As a result of the long duration of the therapy, fear for high pill burden, adverse effects and low perceived risk since the patient has not yet acquired active TB, this may influence adherence. And yet for optimal outcomes of IPT adherence is key. General objective To study the prevalence of IPT adherence and its associated factors among HIV-positive soldiers on ART at General Military Hospital, Bombo. Methods This study was a hospital based cross-sectional study which was conducted in the HIV clinic in Bombo Military Hospital, Uganda. Using consecutive sampling method, 300 clients were enrolled into the study from March 2022 to September 2022. Interviewer administered structured questionnaires were used to collect data. Modified Poisson model with robust standard errors was used to assess the factors associated with adherence to IPT treatment among the HIV positive soldiers in the last 28 days of INH prescribed. The adherence was assessed by self-report.