Browsing by Author "Tumwine, James K."
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Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda
Bachou, Hanifa; Tylleskär, Thorkild; Kaddu-Mulindwa, Deogratias H.; Tumwine, James K. (BioMed Central, 2006)BACKGROUND: To establish the magnitude of bacteraemia in severely malnourished children, and describe the types of bacteria and antimicrobial sensitivity by HIV status. METHOD: Isolates were recovered from 76 blood ... -
The contribution of research in advancing health care in Uganda
Faculty of Medicine, Makerere University; Sewankambo, Nelson K.; Tumwine, James K. (2005-11)This is a book of abstracts of the first annual scientific conference organised by the Faculty of Medicine, Makerere University on "the contribution of research in advancing health care in Uganda" at Imperial Beach Resort ... -
Cryptosproridiosis and microsporidiosis in Ugandan children with persistent diarrhea with and without concurrent infection with the Human Immunodeficiency Virus
Tumwine, James K.; Kekitiinwa, Addy; Bakeera-Kitaka, Sabrina; Ndeezi, Grace; Downing, Robert; Feng, Xiaochuan; Akiyoshi, Donna E.; Tzipori, Saul (American Society of Tropical Medicine and Hygiene, 2005)Cryptosporidium spp. and Enterocytozoon bieneusi are enteric pathogens that have emerged as significant causes of persistent diarrhea (PD) in immunologically compromised individuals particularly in association with HIV/AIDS. ... -
Determinants of infant growth in Eastern Uganda: a community-based cross-sectional health study
Engebretsen, Ingunn Marie Stadskleiv; Tylleskär, Thorkild; Wamani, Henry; Karamagi, Charles A. S.; Tumwine, James K. (BioMed Central, 2008-12-22)Background: Child under-nutrition is a leading factor underlying child mortality and morbidity in Sub-Saharan Africa. Several studies from Uganda have reported impaired growth, but there have been few if any community-based ... -
Effect of multiple micronutrient supplementation on survival of HIV-infected children in Uganda: a randomized, controlled trial
Ndeezi, Grace; Tylleskär, Thorkild; Ndugwa, Christopher M.; Tumwine, James K. (BioMed Central, 2010)Background: Micronutrient deficiencies compromise the survival of HIV-infected children in low-income countries. We assessed the effect of multiple micronutrient supplementation on the mortality of HIV-infected children ... -
Emergence of sickle cell gene through migration and intermarriage: A case study
Okwi, A. L.; Byarugaba, Wilson; Parkes, Arthur; Bimenya, Gabriel S.; Othieno, Emmanuel; Tumwine, James K.; Ndugwa, Christopher M. (Africa Journal of Animal and Biomedical Sciences, 2009)Sickle cell disease (SCD) is an inheritable disorder which is very common among persons of equatorial regions including Africa. The evolution of SCD is linked to malaria endemicity in which sickle cell traits are selected for ... -
Factors associated with birth asphyxia among term singleton births at two referral hospitals in Northern Uganda: A cross sectional study
Ayebare, Elizabeth; Hanson, Claudia; Nankunda, Jolly; Hjelmstedt, Anna; Nantanda, Rebecca; Jonas, Wibke; Tumwine, James K.; Ndeezi, Grace (BMC Pregnancy and Childbirth, 2022)Background: Birth asphyxia is one of the leading causes of neonatal mortality worldwide. In Uganda, it accounts for 28.9% of all neonatal deaths. With a view to inform policy and practice interventions to reduce adverse ... -
Fetal heart rate monitoring practices at a public hospital in Northern Uganda – what health workers document, do and say
Ayebare, Elizabeth; Jonas, Wibke; Ndeezi, Grace; Nankunda, Jolly; Hanson, Claudia; Tumwine, James K.; Hjelmstedt, Anna (Global Health Action, 2020-01-20)Background: In Uganda, perinatal mortality is 38 per 1000 pregnancies. One-third of these deaths are due to birth asphyxia. Adequate fetal heart rate (FHR) monitoring during labor may detect birth asphyxia but little is ... -
Genomic survey of the non-cultivatable opportunistic human pathogen, enterocytozoon bieneusi
Akiyoshi, Donna E.; Morrison, Hilary G.; Lei, Shi; Feng, Xiaochuan; Zhang, Quanshun; Corradi, Nicolas; Mayanja, Harriet; Tumwine, James K.; Keeling, Patrick J.; Weiss, Louis M.; Tzipori, Saul (Public Library of Science, 2009-01-09)Enterocytozoon bieneusi is the most common microsporidian associated with human disease, particularly in the immunocompromised population. In the setting of HIV infection, it is associated with diarrhea and wasting syndrome. ... -
Health care workers’ experiences of managing foetal distress and birth asphyxia at health facilities in Northern Uganda
Ayebare, Elizabeth; Ndeezi, Grace; Hjelmstedt, Anna; Nankunda, Jolly; Tumwine, James K.; Hanson, Claudia; Jonas, Wibke (BMC, 2021-01)Background: Birth asphyxia is one of the leading causes of intrapartum stillbirth and neonatal mortality worldwide. We sought to explore the experiences of health care workers in managing foetal distress and birth asphyxia ... -
Infant feeding counselling in Uganda in a changing environment with focus on the general population and HIV-positive mothers - a mixed method approach
Fadnes, Lars T.; Engebretsen, Ingunn Marie S.; Moland, Karen Marie; Nankunda, Jolly; Tumwine, James K.; Tylleskär, Thorkild (BioMed Central, 2010)Background: Health workers’ counselling practices are essential to improve infant feeding practices. This paper will assess how infant feeding counselling was done and experienced by counsellors and mothers in Eastern ... -
Low adherence to exclusive breastfeeding in Eastern Uganda: a community-based cross-sectional study comparing dietary recall since birth with 24-hour recall
Engebretsen, Ingunn Marie S.; Wamani, Henry; Karamagi, Charles A. S.; Semiyaga, Nulu; Tumwine, James K.; Tylleskär, Thorkild (BioMed Central, 2007-03-01)Background: Exclusive breastfeeding is recommended as the best feeding alternative for infants up to six months and has a protective effect against mortality and morbidity. It also seems to lower HIV-1 transmission compared ... -
Monoclonal antibodies against enterocytozoon bieneusi of human origin
Sheoran, Abhineet S.; Feng, Xiaochuan; Singh, Inderpal; Chapman-Bonofiglio, Susan; Kitaka, Sabrina; Hanawalt, Joel; Nunnari, John; Mansfield, Keith; Tumwine, James K.; Tzipori, Saul (American Society for Microbiology, 2005)Enterocytozoon bieneusi is clinically the most significant among the microsporidia infecting humans, causing chronic diarrhea, wasting, and cholangitis in individuals with human immunodeficiency virus/AIDS. The lack of ... -
Mortality among children under five years admitted for routine care of severe acute malnutrition: a prospective cohort study from Kampala, Uganda
Nalwanga, Damalie; Musiime, Victor; Kizito, Samuel; Kiggundu, John Baptist; Batte, Anthony; Musoke, Philippa; Tumwine, James K. (BMC, 2020)Background: Mortality among children under 5 years of age admitted to malnutrition units in sub-Saharan Africa remains high. The burden of HIV infection, a major risk factor for mortality among patients with severe acute ... -
Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial
Nakibuuka, Victoria; Ndeezi, Grace; Nakiboneka, Deborah; Ndugwa, Christopher M.; Tumwine, James K. (BioMed Central, 2009-10-24)Background: Malaria carries high case fatality among children with sickle cell anaemia. In Uganda, chloroquine is used for prophylaxis in these children despite unacceptably high levels of resistance. Intermittent presumptive ... -
Risk factors in hospital deaths in severely malnourished children in Kampala, Uganda
Bachou, Harriet; Tumwine, James K.; Mwadime, Robert K. N; Tylleskär, Thorkild (BioMed Central, 2006-03-16)Background: Although the risk factors for increased fatality among severely malnourished children have been reported, recent information from Africa, during a period of HIV pandemic and constrained health services, remains ... -
Severe malnutrition with and without HIV-1 infection in hospitalised children in Kampala, Uganda: differences in clinical features, haematological findings and CD4+ cell counts
Bachou, Hanifa; Tylleskär, Thorkild; Downing, Robert; Tumwine, James K. (BioMed Central, 2006-10-16)Background: The aim of this study was to describe the clinical features, haematological findings and CD4+ and CD8+ cell counts of severely malnourished children in relation to human immunodeficiency virus (HIV) infection. ... -
Socio-demographic factors related to periodontal status and tooth loss of pregnant women in Mbale district, Uganda
Wandera, Margaret; Okullo, Isaac; Tumwine, James K.; Engebretsen, Ingunn M. S.; Åstrøm, Anne N. (BioMed Central, 2009-07-18)Background: Information on the socio-behavioral distribution of periodontal status and tooth loss in pregnancy emanating from sub Saharan Africa is sparse. This study examined periodontal status and tooth loss in pregnant ... -
Tanrıverdi, S., et al. (2008). Inferences about the global population structures of Cryptosporidium parvum and Cryptosporidium hominis
Tanriverdi, Sultan; Grinberg, Alex; Chalmers, Rachel M; Hunter, Paul R.; Petrovic, Zorana; Akiyoshi, Donna E.; London, Eric; Zhang, Linghui; Tzipori, Saul; Tumwine, James K.; Widmer, Giovanni (American Society for Microbiology, 2008-12)Cryptosporidium parvum and Cryptosporidium hominis are two related species of apicomplexan protozoa responsible for the majority of human cases of cryptosporidiosis. In spite of their considerable public health impact, ... -
An up-date on the prevalence of sickle cell trait in Eastern and Western Uganda.
Okwi, A.L.; Byarugaba, Wilson; Ndugwa, Christopher M.; Parkes, Arthur; Ocaido, Michael; Tumwine, James K. (BioMed Central, 2010)Background: The first survey on sickle cell disease (SCD) done in Uganda in 1949, reported the district of Bundibugyo in Western Uganda to have the highest sickle cell trait (SCT) prevalence (45%). This is believed to be ...